22b Bone Growth and Development Part 2 Biology Diagrams Growth and Development of Bones. Early in the development of a human fetus, the skeleton is made entirely of cartilage. The relatively soft cartilage gradually turns into hard bone through ossification. This is a process in which mineral deposits replace cartilage. Throughout fetal development and into childhood growth and development, bone forms on the cartilaginous matrix. By the time a fetus is born, most of the cartilage has been replaced with bone. Some additional cartilage will be replaced throughout childhood, and some cartilage remains in the adult skeleton. Intramembranous Ossification
The bone remodeling period consists of the duration of the resorption, the osteoclastic reversal (the phase marked by shifting of resorption processes into formative processes), and the formation periods of bone growth and development. The bone remodeling period refers to the average total duration of a single cycle of bone remodeling at any Bones are often considered static structures that only offer structural support (see Image. Parts of a Long Bone). However, bones have many functions, like other organ systems. Besides serving as a framework for soft tissue, bones permit locomotion, protect vital organs, facilitate breathing, play a role in electrolyte homeostasis, and house hematopoietic sites. Bone remodeling continues Bone cells produce fibroblast growth factor 23 (FGF23) and osteocalcin. FGF23 regulates phosphate handling in the kidney and osteocalcin regulates energy and glucose metabolism (see below) (1,2). In this chapter the anatomy and cell biology of bone is described as well as the mechanisms of bone remodeling, development, and growth.
13.12: Growth and Development of Bones Biology Diagrams
Bone cells produce fibroblast growth factor 23 (FGF23) and osteocalcin. FGF23 regulates phosphate handling in the kidney and osteocalcin regulates energy and glucose metabolism (see below) (1,2). In this chapter the anatomy and cell biology of bone is described as well as the mechanisms of bone remodeling, development, and growth. In the early stages of embryonic development, the embryo's skeleton consists of fibrous membranes and hyaline cartilage. By the sixth or seventh week of embryonic life, the actual process of bone development, ossification (osteogenesis), begins. There are two osteogenic pathways—intramembranous ossification and endochondral ossification—but bone is the same regardless of the pathway that
In the early stages of embryonic development, the embryo's skeleton consists of fibrous membranes and hyaline cartilage. By the sixth or seventh week of embryonic life, the actual process of bone development, ossification (osteogenesis), begins. There are two osteogenic pathways—intramembranous ossification and endochondral ossification—but in the end, mature bone is the same regardless
6.4 Bone Formation and Development Biology Diagrams
Throughout fetal development and into childhood growth and development, bone forms on the cartilaginous matrix. By the time a fetus is born, most of the cartilage has been replaced with bone. Some additional cartilage will be replaced throughout childhood, and some cartilage remains in the adult skeleton. Intramembranous Ossification
